Pharmacology 514:
Current Topics in Pharmacology
Journal Club




Instructions for

JClub Archive

Current Topics in Pharmacology
Phcol 514
12:30 PM, Wednesday, April 26, 2006
Room T-473 HSC

Speaker: Edith Wang
Topic: Brawn for Brains: Role of muscle transcription factors in nervous system development


  1. Li M, Linseman DA, Allen MP, Meintzer MK, Wang X, Laessig T, Wierman ME, Heidenreich KA. Myocyte enhancer factor 2A and 2D undergo phosphorylation and caspase-mediated degradation during apoptosis of rat cerebellar granule neurons. J Neurosci. 2001 Sep 1;21(17):6544-52.

  2. Gaudilliere B, Shi Y, Bonni A. RNA interference reveals a requirement for myocyte enhancer factor 2A in activity-dependent neuronal survival. J Biol Chem. 2002 Nov 29;277(48):46442-6. Epub 2002 Sep 13.

  3. Flavell SW, Cowan CW, Kim TK, Greer PL, Lin Y, Paradis S, Griffith EC, Hu LS, Chen C, Greenberg ME. Activity-dependent regulation of MEF2 transcription factors suppresses excitatory synapse number. Science. 2006 Feb 17;311(5763):1008-12.

  4. Shalizi A, Gaudilliere B, Yuan Z, Stegmuller J, Shirogane T, Ge Q, Tan Y, Schulman B, Harper JW, Bonni A. A calcium-regulated MEF2 sumoylation switch controls postsynaptic differentiation. Science. 2006 Feb 17;311(5763):1012-7.

  1. McKinsey TA, Zhang CL, Olson EN. MEF2: a calcium-dependent regulator of cell division, differentiation and death. Trends Biochem Sci. 2002 Jan;27(1):40-7. Review. Erratum in: Trends Biochem Sci 2002 May;57(5):271.

  2. Shalizi AK, Bonni A. Brawn for Brains: The role of MEF2 proteins in the developing nervous system. Curr Top Dev Biol. 2005;69:239-66.

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