Current Topics in Pharmacology
12:30 PM, Wednesday, May 31, 2006
Room T-473 HSC
Speaker: Joseph Beavo
Topic: Why Bother With a New Kidney? Just Cut to the Marrow!
Morigi M, Imberti B, Zoja C, Corna D, Tomasoni S, Abbate M, Rottoli D, Angioletti S, Benigni A, Perico N, Alison M, Remuzzi G. Mesenchymal Stem Cells Are Renotropic, Helping to Repair the Kidney and Improve Function in Acute Renal Failure. J Am Soc Nephrol. 2004 Jul;15(7):1794-804.
Duffield JS, Park KM, Hsiao LL, Kelley VR, Scadden DT, Ichimura T, Bonventre JV. Restoration of tubular epithelial cells during repair of the postischemic kidney occurs independently of bone marrow-derived stem cells. J Clin Invest. 2005 Jul;115(7):1743-55. Epub 2005 Jun 2.
Lin F, Moran A, Igarashi P. Intrarenal cells, not bone marrow-derived cells, are the major source for regeneration in postischemic kidney. J Clin Invest. 2005 Jul;115(7):1756-64.
Sugimoto H, Mundel TM, Sund M, Xie L, Cosgrove D, Kalluri R. Bone-marrow-derived stem cells repair basement membrane collagen defects and reverse genetic kidney disease. Proc Natl Acad Sci U S A. 2006 May 9;103(19):7321-6. Epub 2006 Apr 28.
Krause D, Cantley LG. Bone marrow plasticity revisited: protection or differentiation in the kidney tubule? J Clin Invest. 2005 Jul;115(7):1705-8. Review.
2005-2006 Journal Club Schedule