Pharmacology 514:
Current Topics in Pharmacology
Journal Club

Current Topics in Pharmacology
Phcol 514
12:30 PM, Wednesday, January 31, 2007
Room T-473 HSC


Speaker: Christine Cheah
Topic: Potential rAAV6-microdystrophin Treatment for Duchenne Muscular Dystrophy

References:

1. Gregorevic P, et al. (2006) rAAV6-microdystriphin preserves muscle function and extends lifespan in severely dystrophic mice. Nat Med. 12(7):787.

2. Odom GL, Gregorevic P, and Chamberlain JS. (2007) Viral-mediated gene therapy for the muscular dystrophies: Successes, limitations and recent advances. Biochim Biophys Acta. 1772(2):243.

3. Harper SQ, et al. (2002) Modular flexibility of dystrophin: Implications for gene therapy of Duchenne muscular dystrophy. Nat Med. 8(3):253.

1. Athanasopoulos T, et al. (2004) Recombinant adeno-associated viral (rAAV) vectors as therapeutic tools for Duchenne muscular dystrophy (DMD). Gene Therapy 11:S109.

2. Biggar WD, et al. (2002) Duchenne Muscular Dystrophy: Current Knowledge, Treatment and Future Prospects. Clin Orthop Relat Res 401:88.

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