Pharmacology 514:
Current Topics in Pharmacology
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Current Topics in Pharmacology
Phcol 514
12:30 PM, Wednesday, February 21, 2007
Room T-473 HSC


Speaker: Derek Dirocco
Topic: BDNF expression in Rett Syndrome

References:

  1. Chen, W. G., Q. Chang, et al. (2003). "Derepression of BDNF transcription involves calcium-dependent phosphorylation of MeCP2." Science 302(5646): 885-9.

  2. Zhou, Z., E. J. Hong, et al. (2006). "Brain-specific phosphorylation of MeCP2 regulates activity-dependent Bdnf transcription, dendritic growth, and spine maturation." Neuron 52(2): 255-69.

  3. Chang, Q., G. Khare, et al. (2006). "The disease progression of Mecp2 mutant mice is affected by the level of BDNF expression." Neuron 49(3): 341-8.

  4. Guy, J., J. Gan, et al. (2007). "Reversal of Neurological Defects in a Mouse Model of Rett Syndrome." Science.

Reviews:
  1. Moretti, P. and H. Y. Zoghbi (2006). "MeCP2 dysfunction in Rett syndrome and related disorders." Curr Opin Genet Dev 16(3): 276-81.

  2. Renieri, A., I. Meloni, et al. (2003). "Rett syndrome: the complex nature of a monogenic disease." J Mol Med 81(6): 346-54.

  3. Ballas, N. and G. Mandel (2005). "The many faces of REST oversee epigenetic programming of neuronal genes." Curr Opin Neurobiol 15(5): 500-6.


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