Pharmacology Pharmacology

Current Topics in Pharmacology

12:30 PM, Thursday, October 25, 2007 | Room T-739 HSC
Speaker: Dr. Bruce Tempel
Topic: Ribbons in your Ear

  1. Goutman, J.D., and Glowatzki, E. (2007). Time course and calcium dependence of transmitter release at a single ribbon synapse. Proc Natl Acad Sci U S A 104, 16341-16346.
  2. Roux, I., Safieddine, S., Nouvian, R., Grati, M., Simmler, M.C., Bahloul, A., Perfettini, I., Le Gall, M., Rostaing, P., Hamard, G., et al. (2006). Otoferlin, defective in a human deafness form, is essential for exocytosis at the auditory ribbon synapse. Cell 127, 277-289.
  3. Griesinger, C.B., Richards, C.D., and Ashmore, J.F. (2005). Fast vesicle replenishment allows indefatigable signalling at the first auditory synapse. Nature 435, 212-215.
  4. Khimich, D., Nouvian, R., Pujol, R., Tom Dieck, S., Egner, A., Gundelfinger, E.D., and Moser, T. (2005). Hair cell synaptic ribbons are essential for synchronous auditory signalling. Nature 434, 889-894.
  5. tom Dieck, S., Altrock, W.D., Kessels, M.M., Qualmann, B., Regus, H., Brauner, D., Fejtova, A., Bracko, O., Gundelfinger, E.D., and Brandstatter, J.H. (2005). Molecular dissection of the photoreceptor ribbon synapse: physical interaction of Bassoon and RIBEYE is essential for the assembly of the ribbon complex. The Journal of Cell Biology 168, 825-836.
  1. Moser, T., Neef, A., and Khimich, D. (2006). Mechanisms underlying the temporal precision of sound coding at the inner hair cell ribbon synapse. J Physiol 576, 55-62.
  2. Fuchs, P.A. (2005). Time and intensity coding at the hair cell's ribbon synapse. J Physiol 566, 7-12.
  3. Sterling, P., and Matthews, G. (2005). Structure and function of ribbon synapses. Trends Neurosci 28, 20-29.
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