Pharmacology Pharmacology

Current Topics in Pharmacology

12:30 PM, Thursday, February 21, 2008 | Room T-473 HSC
Speaker: Erica Melief
Topic: It does a body good: Remodeling of ryanodine receptors in the sarcoplasmic reticulum results in "leaky" channels and decreased exercise tolerance in mice
 
Paper to be presented:

  1. Bellinger, A et al. (2008). Remodeling of ryanodine receptor complex causes "leaky" channels: A molecular mechanism for decreased exercise capacity. PNAS 105:6 2198-2202
Suggested Background Reading:
  1. Bannister RA (2007). Bridging the myoplasmic gap: recent developments in skeletal muscle excitation contraction coupling. J Muscle Res Cell Motil. 28:4-5 275-283
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