Current Topics in Pharmacology
12:30 PM, Thursday, October 2, 2008 | Room T-473 HSC
Speaker: Dr. Richard Gardner
Topic: When drugs miss the target: novel strategies to identify off-target effects
- Ericson E, Gebbia M, Heisler LE, Wildenhain J, Tyers M, Giaever G, Nislow C. 2008 Off-target effects of psychoactive drugs revealed by genome-wide assays in yeast. PLoS Genetics 4: e1000151.
- MacDonald ML, Lamerdin J, Owens S, Keon BH, Bilter GK, Shang Z, Huang Z, Yu H, Dias J, Minami T, Michnick SW, Westwick JK. 2006. Identifying off-target effects and hidden phenotypes of drugs in human cells. Nature Chemical Biology 2: 329-337.