Pharmacology Pharmacology

Current Topics in Pharmacology

12:30 PM, Thursday, November 13, 2008 | Room T-473 HSC
Speaker: Nick Robin
Topic: Synergistic neuroprotective effects of Lithium and HDAC inhibitors
Papers To Be Presented:

  1. Feng HL, Leng Y, Ma CH, Zhang J, Ren M, Chuang DM. Combined lithium and valproate treatment delays disease onset, reduces neurological deficits and prolongs survival in an amyotrophic lateral sclerosis mouse model. Neuroscience. 2008 Aug 26;155(3):567-72. Epub 2008 Jun 21. PMID: 18640245
  2. Leng Y, Liang MH, Ren M, Marinova Z, Leeds P, Chuang DM. Synergistic neuroprotective effects of lithium and valproic acid or other histone deacetylase inhibitors in neurons: roles of glycogen synthase kinase-3 inhibition. J Neurosci. 2008 Mar 5;28(10):2576-88. PMID: 18322101
  1. Chuang DM. The antiapoptotic actions of mood stabilizers: molecular mechanisms and therapeutic potentials. Ann N Y Acad Sci. 2005 Aug;1053:195-204. Review. PMID: 16179524

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