Current Topics in Pharmacology
12:30 PM, Thursday, February 18, 2010 | Room T-531 HSC
Speaker: Nick Robin
Topic: Activity Based Protein Profiling: more cool technology from the Cravatt Lab
- Bachovchin DA, Brown SJ, Rosen H, and Cravatt BF. 2009. Identification of selective inhibitors of uncharacterized enzymes by high-throughput screening with fluorescent activity-based probes. Nature Biotechnology 27: 387-394.
- Jessani N, Niessen S, BinQing QW, Nicolau M, Humphrey M, Youngran J, Wonshik H, Dong-Young N, Yates III JR, Jeffrey SS, and Cravett BF. 2005. A streamlined platform for high-content functional proteomics of primary human specimens. Nature Methods 2: 691-697.
- Barglow KT, and Cravatt BF. 2007. Activity-based protein profiling for the functional annotation of enzymes. Nature Methods 4: 822-827.