Pharmacology Pharmacology

Current Topics in Pharmacology

12:30 PM, Thursday, March 4, 2010 | Room T-531 HSC
Speaker: Ning Zheng
Topic: Let theTail Lead the Way - How to Localize A Tail-anchored Transmembrane Protein.
 
References:

  1. Stefanovic S, Hegde RS. 2007. Identification of a targeting factor for posttranslational membrane protein insertion into the ER. Cell. 128:1147-59.
  2. Schuldiner M, Metz J, Schmid V, Denic V, Rakwalska M, Schmitt HD, Schwappach B, Weissman JS. 2008. The GET complex mediates insertion of tail-anchored proteins into the ER membrane. Cell 134:634-45.
  3. Mateja A, Szlachcic A, Downing ME, Dobosz M, Mariappan M, Hegde RS, Keenan RJ. 2009. The structural basis of tail-anchored membrane protein recognition by Get3. Nature 461:361-6.

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