Pharmacology Pharmacology

Current Topics in Pharmacology

12:30 PM, Thursday, May 26, 2011 | Room D-423 HSB
Speaker: Jim Ruble
Topic: What the heck is a rhomboid? Inhibitor development using HTS and SAR to study rhomboid intramembrane proteases.
Paper to be presented:

    Pierrat OA, Strisovsky K, Christova Y, Large J, Ansell K, Bouloc N, Smiljanic E, Freeman M.2011. Monocyclic β-Lactams Are Selective, Mechanism-Based Inhibitors of Rhomboid Intramembrane Proteases. ACS Chem Biol. 2011 Apr 15;6(4):325-35. Epub 2011 Jan 12.
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