Pharmacology 514:
Current Topics in Pharmacology
Journal Club

Current Topics in Pharmacology
Phcol 514
12:30 PM, Wednesday, October 8, 1997
Room T-530/530A HSC

Speaker: Amanda Kalaydjian
Topic: Welcome home: p53 finds a brother in newly discovered p73

References:

1. Caron, C., Peter, M., van Sluis, P., Speleman, Frank, de Kraker, J., Laureys, G., Michon, J., Brugieres, L., Voute, P.A., Westerveld, A., Slater, R., Delattre, O., Versteeg, R. (1995). Evidence for two tumour suppressor loci on chromosomal band 1p35-36 involoved in neuroblastoma: on probably imprinted, another associated with N-myc amplification. Human Molecular Genetics 4:535-539.

2. Donehourer, L.A., Harvey, M., Slagle, B.L., McArthur, M.J., Montgomery Jr., C.A., Butel, J.S., Bradley, A. (1992). Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours. Nature 19:215-221.

3. Kaghad, M., Bonnet, H., Yang, A., Creancier, L., Biscan, J.C., Valent, A., Minty, A., Chalon, P., Lelias, J.M., Dumont, X., Ferrara, P., McKeon, I., Caput, D. (1997). Monoallelically Expressed Gene Related to p53 at 1p36, a Region Frequently Deleted in Neuroblastoma and Other Human Cancers. Cell 90:809-819.

4. Ohgaki, H., Eibi, R.H., Schwab, M., Reichel, M.B., Mariani, L., Gehring, M., Peterson, I., Höll, T., Wiestler, O.D., Kleinues, P. (1993). Mutations of the p53 Tumor Suppressor Gene in Neoplasms of the Human Nervous System. Molecular Carcinogenesis 8:74-80.

5. Jost, C.A., Marin, M.C., Kaelin Jr., W.G. (1997). p73 is a human p53-related protein that can induce apoptosis. Nature 389:191-194.

Reviews:

1. Ko, L.J., and Prives, C. (1996). p53-puzzle and paradigm. Genes and Development 10:1054-1072.

2. Levine, A.J. (1997). p53-the Cellular Gatekeeper for Growth and Division. Cell 88:323-331.

3. Oren, M. (1997). Lonely No More: p53 Finds Its Kin in a Tumor Suppressor Haven. Cell 90:829-832.

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