Pharmacology 514:
Current Topics in Pharmacology
Journal Club




Instructions for

JClub Archive

Current Topics in Pharmacology
Phcol 514
12:30 PM, Wednesday, November 19, 1997
Room T-530/530A HSC

Speaker: Brian Hale
Topic: Happy TrkA Day: Being Thankful for NGF Retrograde Signaling and CREB Phosphorylation


  1. Hendry IA, Stach R, Herrup K. Characteristics of the retrograde axonal transport system for nerve growth factor in the sympathetic nervous system. Brain Res 1974 Dec 20;82(1):117-128.

  2. Palmatier MA, Hartman BK, Johnson EM Jr. Demonstration of retrogradely transported endogenous nerve growth factor in axons of sympathetic neurons. J Neurosci 1984 Mar;4(3):751-756.

  3. Kaplan DR, Martin-Zanca D, Parada LF. Tyrosine phosphorylation and tyrosine kinase activity of the trk proto-oncogene product induced by NGF. Nature 1991 Mar 14;350(6314):158-160.

  4. Kaplan DR, Hempstead BL, Martin-Zanca D, Chao MV, Parada LF. The trk proto-oncogene product: a signal transducing receptor for nerve growth factor. Science 1991 Apr 26;252(5005):554-558.

  5. Senger DL, Campenot RB. Rapid retrograde tyrosine phosphorylation of trkA and other proteins in rat sympathetic neurons in compartmented cultures. J Cell Biol 1997 Jul 28;138(2):411-421.

  6. Riccio A, Pierchala BA, Ciarallo CL, Ginty DD. An NGF-TrkA-mediated retrograde signal to transcription factor CREB in sympathetic neurons. Science 1997 Aug 22;277(5329):1097-1100.

  7. Bhattacharyya A, Watson FL, Bradlee TA, Pomeroy SL, Stiles CD, Segal RA. Trk receptors function as rapid retrograde signal carriers in the adult nervous system. J. Neurosci 1997 Sep 15;17(18):7007-7016.

  8. Kaplan DR, Stephens RM. Neurotrophin signal transduction by the Trk receptor. J Neurobiol 1994 Nov;25(11):1404-1417.

  9. Barbacid M. Neurotrophic factors and their receptors. Curr Opin Cell Biol 1995 Apr;7(2):148-155.

1997-1998 Journal Club Archive

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