Pharmacology 514:
Current Topics in Pharmacology
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Current Topics in Pharmacology
Phcol 514
12:30 PM, Wednesday, November 19, 1997
Room T-530/530A HSC

Speaker: Brian Hale
Topic: Happy TrkA Day: Being Thankful for NGF Retrograde Signaling and CREB Phosphorylation

References:

  1. Hendry IA, Stach R, Herrup K. Characteristics of the retrograde axonal transport system for nerve growth factor in the sympathetic nervous system. Brain Res 1974 Dec 20;82(1):117-128.

  2. Palmatier MA, Hartman BK, Johnson EM Jr. Demonstration of retrogradely transported endogenous nerve growth factor in axons of sympathetic neurons. J Neurosci 1984 Mar;4(3):751-756.

  3. Kaplan DR, Martin-Zanca D, Parada LF. Tyrosine phosphorylation and tyrosine kinase activity of the trk proto-oncogene product induced by NGF. Nature 1991 Mar 14;350(6314):158-160.

  4. Kaplan DR, Hempstead BL, Martin-Zanca D, Chao MV, Parada LF. The trk proto-oncogene product: a signal transducing receptor for nerve growth factor. Science 1991 Apr 26;252(5005):554-558.

  5. Senger DL, Campenot RB. Rapid retrograde tyrosine phosphorylation of trkA and other proteins in rat sympathetic neurons in compartmented cultures. J Cell Biol 1997 Jul 28;138(2):411-421.

  6. Riccio A, Pierchala BA, Ciarallo CL, Ginty DD. An NGF-TrkA-mediated retrograde signal to transcription factor CREB in sympathetic neurons. Science 1997 Aug 22;277(5329):1097-1100.

  7. Bhattacharyya A, Watson FL, Bradlee TA, Pomeroy SL, Stiles CD, Segal RA. Trk receptors function as rapid retrograde signal carriers in the adult nervous system. J. Neurosci 1997 Sep 15;17(18):7007-7016.

  8. Kaplan DR, Stephens RM. Neurotrophin signal transduction by the Trk receptor. J Neurobiol 1994 Nov;25(11):1404-1417.

  9. Barbacid M. Neurotrophic factors and their receptors. Curr Opin Cell Biol 1995 Apr;7(2):148-155.


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