Current Topics in Pharmacology
12:30 PM, Wednesday, January 7, 1998
Room T-530/530A HSC
Speaker: Charles Chavkin
Topic: Tales from Two Cities
Junkies in New Haven:
Carlezon, W.A., Boundy, V.A., Haile, C.N., Lane, S.B., Kalb, R.G., Neve, R.L., Nestler, E.J. (1997) Sensitization to morphine induced by viral-mediated gene transfer. Science 277:812-814
Carlezon, W.A., Wise, R.A. (1996) Microinjections of phencyclidine (PCP) and related drugs into nucleus accumbens shell potentiate medial forebrain bundle brain stimulation reward. Psychopharmacology 128:413-420.
Carlezon, W.A., Wise, R.A. (1996) Rewarding actions of phencyclidine and related drugs in nucleus accumbens shell and frontal cortex. Journal of Neuroscience 16:3112- 3122.
Sadomasochists in San Francisco:
Malmberg, A.B., Chen, C., Tonegawa, S., Basbaum, A.I. (1997) Preserved acute pain and reduced neuropathic pain in mice lacking PKC gamma. Science 278:279-283.
Malmberg, A.B., Brandon, E.P., Idzerda, R.L., Liu, H.T., McKnight, G.S. Basbaum, A.I. (1997) Diminished inflammation and nociceptive pain with preservation of neuropathic pain in mice with a targeted mutation of the type I regulatory subunit of cAMP-dependent protein kinase. Journal of Neuroscience 17:7462- 7470.
Malmberg, A.B., Yaksh, T.L. (1995) Cyclooxygenase inhibition and the spinal release of prostaglandin E2 and amino acids evoked by paw formalin injection: a microdialysis study in unanesthetized rats. Journal of Neuroscience 15:2768-2776.
Malmberg, A.B., Yaksh, T.L. (1994) Voltage-sensitive calcium channels in spinal nociceptive processing: blockade of N- and P-type channels inhibits formalin-induced nociception. Journal of Neuroscience 14:4882-4890.
Malmberg, A.B., Yaksh, T.L. (1992) Hyperalgesia mediated by spinal glutamate or substance P receptor blocked by spinal cyclooxygenase inhibition. Science 257:1276-1279.
Nestler, E.J. (1997) Molecular mechanisms of opiate and cocaine addiction. Current Opinion in Neurobiology 7:713-719.
Koob, G.F., Nestler, E.J.( 1997) The neurobiology of drug addiction. Journal of Neuropsychiatry and Clinical Neurosciences 9:482-497.
Wise, R.A. (1996) Neurobiology of addiction. Current Opinion in Neurobiology 6:243-251.
1997-1998 Journal Club Archive