Pharmacology 514:
Current Topics in Pharmacology
Journal Club




Instructions for

JClub Archive

Current Topics in Pharmacology
Phcol 514
12:30 PM, Wednesday, March 4, 1998
Room T-530/530A HSC

Speaker: Rachel Squillace
Topic: Three unique and cool mechanisms of translational regulation


  1. Rivera-Pomar R, Niessing D, Schmidt-Ott U, Gehring WJ, Jackle H. RNA binding and translational suppression by bicoid. Nature 1996 Feb 22;379(6567):746-749.

  2. Dubnau J, Struhl G. RNA recognition and translational regulation by a homeodomain protein. Nature 1996 Feb 22;379(6567):694-699.

  3. Vagner S, Touriol C, Galy B, Audigier S, Gensac MC, Amalric F, Bayard F, Prats H, Prats AC. Translation of CUG- but not AUG-initiated forms of human fibroblast growth factor 2 is activated in transformed and stressed cells. J Cell Biol 1996 Dec;135(5):1391-1402.

  4. Nanbru C, Lafon I, Audigier S, Gensac MC, Vagner S, Huez G, Prats AC. Alternative translation of the proto-oncogene c-myc by an internal ribosome entry site. J Biol Chem 1997 Dec 19;272(51):32061-32066.

  5. Gingras AC, Kennedy SG, O'Leary MA, Sonenberg N, Hay N. 4E-BP1, a repressor of mRNA translation, is phosphorylated and inactivated by the Akt(PKB) signaling pathway. Genes Dev 1998 Feb 15;12(4):502-513.

  6. Vries RG, Flynn A, Patel JC, Wang X, Denton RM, Proud CG. Heat shock increases the association of binding protein-1 with initiation factor 4E. J Biol Chem 1997 Dec 26;272(52):32779-32784.


  1. Carr K. Gene Expression. RNA bound to silence. Nature 1996 Feb 22;379(6567):676.

  2. Chan SK, Struhl G. Sequence-specific RNA binding by bicoid. Nature 1997 Aug 14;388(6643):634.

1997-1998 Journal Club Archive

Announcements | Schedule | Faculty | Instructions for Speakers | JClub Archives