Pharmacology 514:
Current Topics in Pharmacology
Journal Club


Announcements

Schedule

Faculty

Instructions for
Speakers


JClub Archive

Current Topics in Pharmacology
Phcol 514
12:30 PM, Wednesday, December 2, 1998
Room T-530/530A HSC

Speaker: Joe Beavo
Topic: Caveolae, 'Little Caves:' Roles in Signal Transduction

References:

  1. Chang, W. J., Rothberg, K. G., Kamen, B. A., and Anderson, R. G. (1992). Lowering the cholesterol content of MA104 cells inhibits transport of folate. J Cell Biol 118, 63-9.

  2. Feron, O., Kelly, R. A., and Michel, T. (1998). Modulation of the eNOS-caveolin interaction in cardiac myocytes. Implications for regulation of heart rate. J Biol Chem 273, 30249-54.

  3. Furuchi, T., and Anderson, R. G. (1998). Cholesterol depletion of caveolae causes hyperactivation of extracellular signal-related kinase (ERK). J Biol Chem 273, 21099-104.

  4. Garcia-Cardena, G., Lisanti, M. P., and Sessa, W. C. (1997). Interaction between NOS and caveolin. Significance of the NOS caveolin binding domain in vivo. JBC 272, 25437-40.

  5. Garcia-Cardena, G., Oh, P., Liu, J., Schnitzer, J. E., and Sessa, W. C. (1996). Targeting of NOS to caveolae via palmitoylation: implications for nitric oxide signaling. PNAS 93, 6448-53.

  6. Liu, J., Garcia-Cardena, G., and Sessa, W. C. (1996). Palmitoylation of eNOS is necessary for optimal release of NO: implications for caveolae localization. Biochemistry 35, 13277-81.

  7. Michel, J. B., Feron, O., Sacks, D., and Michel, T. (1997). Reciprocal regulation of endothelial nitric-oxide synthase by Ca2+- calmodulin and caveolin. J Biol Chem 272, 15583-6.

  8. Pike, L. J. and Miller, J. M. (1998) Cholesterol depletion delocalizes phosphatidylinositol bisphosphate and inhibits hormone-stimulated PI turnover. J Biol Chem. 273:22298-304

  9. Rothberg, K. G., Ying, Y. S., and Anderson, R. G. (1990). Cholesterol controls clustering of the GPI-anchored membrane receptor for 5-methyltetrahydrofolate. J Cell Biol 111, 2931-8.


1998-1999 Journal Club Archive
Other
Pharmacology
Courses

Announcements | Schedule | Faculty | Instructions for Speakers | JClub Archives