Pharmacology 514:
Current Topics in Pharmacology
Journal Club




Instructions for

JClub Archive

Current Topics in Pharmacology
Phcol 514
12:30 PM, Wednesday, January 6, 1999
Room T-530/530A HSC

Speaker: Bill Catterall
Topic: SNARE Proteins and Exocytosis: do they or don't they?


  1. Hanson, P.I., Heuser, J.E., and Jahn, R. (1997) Neurotransmitter release - four years of SNARE complexes. Curr. Opin. Neurobiol. 7:310-315. SNARE Proteins Cause Vesicular Fusion in Vitro

  2. Weber, T., Zemelman, B.V., McNew, J.A. Westermann, B., Gmachl, M., Parlati, F., Söllner, T.H., and Rothman, J.E. (1998) SNAREpins: Minimal machinery for membrane fusion. Cell 92:759-772. Formation of Specialized Parallel Coiled Coils Drives SNARE Protein Interaction

  3. Hanson, P.I., Roth, R., Morisaki, H., Jahn, R., and Heuser, J.E. (1997) Structure and conformational changes in NSF and its membrane receptor complexes visualized by quick-freeze/deep-etch electron microscopy. Cell 90:523-535.

  4. Lin, R.C. and Scheller, R.H. (1997) Structural organization of the synaptic exocytosis core complex. Neuron 19:1087-1094.

  5. Sutton, R.B.,. Fasshauer, D., Jahn, R., and Brunger, A.T. (1998) Crystal structure of a SNARE complex involved in synaptic exocytosis at 2.4  resolution. Nature 395:347-353.

    But Calcium and Calmodulin Are Required For Yeast Vacuole Fusion After SNARE Protein Dissociation

  6. Mayer, A., Wickner, W., and Hass, A. (1996) Sec18p (NSF)-driven release of Sec17p (a-SNAP) can precede docking and fusion of yeast vacuoles. Cell 85:83-94.

  7. Nichols, B.J., Ungermann, C., Pelham, H.R.B., Wickner, W.T., and Hass, A. (1997) Homotypic vacuolar fusion mediated by t- and v-SNAREs. Nature 387:199-202.

  8. Sato, K. and Wickner, W. (1998) Functional reconstitution of Ypt7p GTPase and a purified vacuole SNARE complex. Science 281:700-702.

  9. Ungermann, C., Sato, K., and Wickner, W. (1998) Defining the functions of trans-SNARE pairs. Nature 396:543-548.

  10. Peters, C. and Mayer, A. (1998) Ca2+/calmodulin signals the completion of docking and triggers a late step of vacuole fusion. Nature 396:575-580.

1998-1999 Journal Club Archive

Announcements | Schedule | Faculty | Instructions for Speakers | JClub Archives