Pharmacology 514:
Current Topics in Pharmacology
Journal Club

Current Topics in Pharmacology
Phcol 514
12:30 PM, Wednesday, March 3, 1999
Room T-530/530A HSC

Speaker: Laird Sheldahl
Topic: PKA-independent CRE-CREB activities

References:

1. Bito H., Deisseroth K., Tsein R.W. (1996) CREB phosphorylation and dephosphorylation: a Ca2+- and stimulus duration-dependent switch for hippocampal gene expression. Cell 87:1203-1214.

2. Chawla S., Hardingham G.E., Quinn D.R., Bading H. (1998) CBP: a signal-regulated transcriptional coactivator controlled by nuclear calcium and CaM kinase IV. Science 281:1505-1509.

3. Deisseroth K., Bito H., Tsien R.W. (1996) Signaling from synapse to nucleus: postsynaptic CREB phosphorylation during multiple forms of hippocampal synaptic plasticity. Neuron 16:89-101.

4. Ghosh A., Greenberg M. (1995) Calcium signaling in neurons: molecular mechanisms and cellular consequences. Science 268:239-246.

5. Gudi T., Huvar I., Meinecke M., Lohman S.M., Boss G.R., Pilz R.B. (1995) Regulation of gene expression by cGMP-dependent protein kinase. Journal of Biological Chemistry 271(9):4597-4600.

6. Hardingham G.E., Chawla S., Johnson C., Bading H. (1997) Distinct functions of nuclear and cytoplasmic calcium in the control of gene expression. Nature 385:260-265.

7. Impey S., Wayman G., Wu Z., Storm D.R. (1994) Type I adenylyl cyclase functions as a coincidence detector for control of cyclic AMP Response Element-mediated transcription: synergistic regulation of transcription by Ca2+ and Isoproterenol. Molecular and Cellular Biology 14(12):8272-8281.

8. Xie H., Wang Z., Rothstein T. (1996) Signaling pathways for antigen receptor-mediated induction of transcription factor CREB in B lymphocytes. Cellular Immunology 169:264-270.

1. Ginty, David D. Calcium regulation of gene expression: isn't that spatial? (1997) Neuron 18:183-286.

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