Pharmacology 514:
Current Topics in Pharmacology
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Current Topics in Pharmacology
Phcol 514
12:30 PM, Wednesday, April 21, 1999
Room T-530/530A HSC

Speaker: Dale Chenault
Topic: C/EBPS and Immunity

References:

  1. Yamanka, R., Barlow, C., Lekstom-Himes, J., Castialla, L.H., Liu, P.P., Eckhause, M., Decker, T., Wynshaw-Boris, A., and Xanthopoulos, K.G. (1997) Impaired granulupoiesis, myelodysplasia, and early lethality in CCAAT/enchancer binding protein e-deficient mice. Proc. Natl. Acad. Sci. U.S.A. 94:13187-13192.

  2. Matsumoto, M., Sakao, Y., and Akira, S. (1998) Inducible expression of nuclear factor IL-6 increases endogenous gene expression of macrophage inflammatory protein 1a, osteopontin, and CD14 in a monocytic leukemia cell line. Int. Immunol. 10:1825-1835.

  3. Ruocco, M.R., Chen, X., Ambrosino, C., Dragonetti, E., Liu, W., Mallardo, M., De Falco, G., Palmieri, C., Franzoso, G., Quinto, I., Venuto, S., and Scala, G. (1996) Regulation of HIV-1 long terminal repeats by interaction of C/EBP (NF-IL6) and NF-kappaB/Rel transcription factors. J. Biol. Chem. 271: 22479-22486.

  4. Henderson, A.J. and Calame, K.L. (1997) CCAAT/enhancer binding protein (C/EBP) sites are required for HIV-1 replication in primary macrophages but not CD4+ T cells. Proc. Natl. Acad. Sci. U.S.A. 94:8714-8719.

  5. Yamanaka, R., Kim, G.D., Radomska, H.S., Himes, J.L., Smith, L.T., Antoson, P., Tenen, D.G., Xanthopoulos, K.G. (1997) CCAAT/enhancer binding protein epsilon is preferentially up-regulated during granulocytic differentiation and its functional versatality is determined by alternative use of promoters and differential splicing. Proc. Natl. Acad. Sci. U.S.A. 94:6462-6467.

  6. Zhang, D.E., Zhang, P., Wang, N.D., Hetherington, C.J., Darlington, G.J., and Tenen, D.G. (1997) Absence of granulocyte colony stimulating factor signaling and neutrophil development in CCAAT enhancer binding protein a-deficient mice. Proc. Natl. Acad. Sci. U.S.A. 94:569-574.

  7. Tinnell, S., Jacobs-Helber, S.M., Sterneck, E., Sawyer, S.T., and Conrad, D.H. (1998) STAT6, NFkB, and C/EBP in CD23 expression and IgE production. Int. Immunol. 10:1529-1538.

  8. Ohno, H., Kancho, S., Kobayashi, K., and Murakami, S. (1997) Human Hepatitis B enhancer 1 is responsive to Human Interleuklin-6. J. Med. Virol. 52:413-418.



Reviews:
  1. Landschulz, W.H., Johnson, P.F., and McKnight, S.L. (1989) The Leucine Zipper: A Hypothetical Structure Common to a New Class of DNA Binding Proteins. Science 24:1759-1764.

  2. Poli, V. (1998) The Role of C/EBP Isoforms in the control of Inflammatory and Native Immunity Functions. J. Biol. Chem. 273:29279-29282.


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