Pharmacology 514:
Current Topics in Pharmacology
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Current Topics in Pharmacology
Phcol 514
12:30 PM, Wednesday, April 7, 1999
Room T-530/530A HSC

Speaker: Jane Gunther
Topic: P2X receptors times two. Two independent labs report on the activity of P2X channels to change their ionic selectivity

References:

  1. Virginio C, MacKenzie A, Rassendren FA, North RA, and Surprenant A (1999) Pore dilation of neuronal P2X receptor channels. Nature Neurosci. 2:315-321.

  2. Khakh BS, Bao XR, Labarca C, and Lester HA (1999) Neuronal P2X transmitter-gated cation channels change their ion selectivity in seconds. Nature Neurosci. 2:322-330.

  3. Valera S, Hussy N, Evans RJ, Adami N, North RA, Surprenant A, and Buell G (1994) A new class of ligand-gated ion channel defined by P2X receptor for extracellular ATP. Nature 371:516-523.

  4. Surprenant A, Rassendren F, Kawashima E, North RA, and Buell G (1996) The Cytolytic P2Z Receptor for Extracellular ATP Identified as a P2X Receptor (P2X7). Science 272:735-738.

  5. Evans BJ, Lewis C, Virginio C, Lundstrom K, Buell G, Surprenant A, and North RA (1996) Ionic permeability of, and divalent cation effects on, two ATP-gated cation channels (P2X receptors) expressed in mammalian cells. J. Physiol. 497:413-422.

  6. Virginio C, North RA, and Surprenant A (1998) Calcium permeability and block at homomeric and heteromeric P2X2 and P2X3 receptors, and P2X receptors in rat nodose neurones. J. Physiol. 510:27-35.

  7. Gu JG and MacDermott AB (1997) Activation of ATP P2X receptors elicits glutamate release from sensory neuron synapses. Nature 389:749-753.



Reviews:
  1. North RA and Barnard EA (1997) Nucleotide receptors. Curr. Opin. Neurobiol. 7:346-357.


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