Pharmacology 514:
Current Topics in Pharmacology
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Current Topics in Pharmacology
Phcol 514
12:30 PM, Wednesday, May 12, 1999
Room T-530/530A HSC

Speaker: Rejean Idzerda
Topic: Locally regulated translation in dendrites (a mechanism)

References:

  1. Steward O, Wallace CS, Lyford GL, and Worley PF. (1998) Synaptic Activation Causes the mRNA for the IEG Arc to Localize Selectively near Activated Postsynaptic Sites on Dendrites. Neuron 21:741-751.

  2. Wu L, Wells D, Tay J, Mendis D, Abbott M-A, Barnitt A, Quinlan E, Heynen A, Fallon JR, and Richter JD. (1998) CPEB-Mediated Cytoplasmic Polyadenylation and the Regulation of Experience-Dependent Translation of a-CaMKII mRNA at Synapses. Neuron 21:1129-1139.

  3. Ouyang Y, Kantor D, Harris KM, Schuman EM, and Kennedy MB. (1997) Visualization of the Distribution of Autophosphorylated Calcium/Calmodulin-Dependent Protein Kinase II after Tetanic Stimulation in the CA1 Area of the Hippocampus. J. Neurosci. 17:5416-5427.

  4. Kang H and Schuman EM. (1996) A Requirement for Local Protein Synthesis in Neurotrophin-Induced Hippocampal Synaptic Plasticity. Science 273:1402-1406.

  5. Steward O and Levy WB. (1982) Preferential Localization of Polyribosomes Under the Base of Dendritic Spines in Granule Cells of the Dentate Gyrus. J. Neurosci.2:284-291.

Reviews:
  1. Huang EP. (1999) Synaptic Plasticity: Regulated translation in dendrites. Curr. Biol. 9:R168-R170.

  2. Kuhl D and Skehel P. (1998) Dendritic localization of mRNAs. Curr. Opin. Neurobiol. 8:600-606.


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