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Current Topics in Pharmacology
Phcol 514
12:30 PM, Wednesday, September 30, 1998
Room T-530/530A HSC
Speaker: G. Stanley McKnight
Topic: Dancing to the ras-raf-rap
References:
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York RD, Yao H, Dillon T, Ellig CL, Eckert SP, McCleskey EW, Stork PJ. (1998) Rap1 mediates sustained MAP kinase activation induced by nerve growth factor. Nature 392 (6676):622-626
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Vossler MR, Yao H, York RD, Pan MG, Rim CS, Stork PJ. (1997) cAMP activates MAP kinase and Elk-1 through a B-Raf- and Rap1-dependent pathway. Cell 89 (1):73-82
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Yao H, York RD, Misra-Press A, Carr DW, Stork PJ. (1998) The cyclic adenosine monophosphate-dependent protein kinase (PKA) is required for the sustained activation of mitogen-activated kinases and gene expression by nerve growth factor. J Biol Chem 273 (14):8240-8247
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Posern G, Weber CK, Rapp UR, Feller SM. (1998) Activity of rap1 is regulated by bombesin, cell adhesion, and cell density in NIH3T3 fibroblasts. J Biol Chem 273 (38):24297-24300
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Altschuler DL, Ribeiro-Neto F. (1998) Mitogenic and oncogenic properties of the small G protein Rap1b. Proc Natl Acad Sci USA 95 (13):7475-7479
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Okada S, Matsuda M, Anafi M, Pawson T, Pessin JE. (1998) Insulin regulates the dynamic balance between Ras and Rap1 signaling by coordinating the assembly states of the Grb2-SOS and CrkII-C3G complexes. EMBO J 17 (9):2554-2565
Reviews:
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Marshall CJ. (1998) Nature 392 (6676):553-554
1998-1999 Journal Club Archive
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