Lecture No. |
Day |
Date |
Topics |
Lecturer |
| 1 |
M |
Nov 5 |
Introduction to 2 messenger signal transduction systems -
-The cAMP signal transduction system |
D. Storm |
| 2 |
W |
Nov 7 |
General principles of G protein coupling
Calcium/CaM signaling |
D. Storm |
| 3 |
F |
Nov 9 |
Cross talk between calcium and cAMP regulatory systems
- Olfactory signal transduction & circadian biology
| D. Storm |
| |
F |
Nov 12 |
Veteran's Day Holiday |
|
|
|
|
|
|
| 4 |
M |
Nov 14 |
Proteolysis and signal transduction:
- WNT -1 signaling |
R. Moon |
| 5 |
W |
Nov 16 |
Proteolysis and signal transduction:
- Hedgehog and Notch signaling pathways. |
R. Moon |
| 6 |
M |
Nov 19 |
Presentation and discussion of current paper on Wnt signaling |
R. Moon |
| 7 |
W |
Nov 21 |
Introduction to tyrosine receptor kinase cascades:
- Map kinase cascades |
J. Beavo |
|
F |
Nov 23 |
Thanksgiving Break |
|
| 8 |
F |
Nov 26 |
Tyrosine Receptor Kinase pathways (continued)
- GEFs & GAFs |
J. Beavo |
| 9 |
M |
Nov 28 |
Tyrosine receptor kinase pathways and cAMP
Insulin, IGF-1, IRS signaling |
J. Beavo |
| 10 |
W |
Nov 30 |
Insulin, IGF-1, IRS signaling (continued)
Introduction to Cytokine/Jak/Stat signaling pathways |
J. Beavo |
|
|
|
|
|
| 11 |
M |
Dec 3 |
Cytokine/Jak/Stat signaling pathways (continued) |
J Beavo |
| 12 |
W |
Dec 5 |
Complex Systems: Nitric oxide/CO/cGMP signaling pathways:
- Mechanism of action of Viagra |
J. Beavo |
| 13 |
F |
Dec7 |
Complex systems: signaling pathways in developmental biology |
R Moon |
| 14 |
M |
Dec10 |
Complex systems: molecular basis of synaptic plasticity
and its relationship to learning and memory |
D. Storm |
| 15 |
W |
Dec 12 |
Complex systems: Turning off the signal:
- Regulation by reversal of signaling pathways. |
J. Beavo |
|
M |
Dec 17?? |
Final Exam |
|