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QSCI 381B: Introduction to Probability and Statistics

 

 

The objective of this course is to introduce students to the fundamentals of probability and inferential statistics, within the context of biological problems.

 

We will first learn how to summarize data using graphical and tabular methods. This is the first step when analyzing whether a given data set provides support for or against a hypothesis regarding how some biological process operates. We will learn how to calculate means, standard deviations, and confidence intervals, as well as how to construct histograms and other graphical data summaries.

 

The second section of the course is an introduction to probability theory. We will learn how to define and manipulate probabilities and how probability relates to the statistical distributions used in inferential statistics. The probability distributions covered during the course will include the normal, t, chi-square, Poisson, and binomial distributions.

 

The third section of the course focuses on testing biological hypotheses. We will first explore how to state biological hypotheses in a way that they can be tested using field data. The remainder of this section will introduce students to the principles of statistical hypothesis testing, including how to define Type I and Type II error rates, how to define rejection regions for statistical tests, and how to select and then apply a series of commonly applied statistical tests. The statistical tests that will be covered will include:

 

·        tests based on one sample from a population;

·        tests based on a sample from each of two populations; and

·        test which assess whether two variables are correlated and if so how.

 

The concepts will be illustrated by applying them to problems from the biological sciences. Whenever possible, the methods will be illustrated using EXCELTM, but students will also be expected to be able to apply the methods using a hand-held calculator.

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