Short-Term Assay Review
Credit/No Credit Class Assignment
Depending on your biological background, you should choose a short-term
assay to review. For those students with limited biological background,
the instructors would suggest assay #1, for those students that are more
comfortable with their biological knowledge, please choose from the other
assays. The instructors will provide the papers you are to review for each
assay. You should not do an extra external literature search.
Your review should include:
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Cells or organisms utilized
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Brief description of experimental protocol
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Biological endpoints monitored
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Chemicals tested
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Usefulness:
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Cost, ease of methodology, space, time and laboratory requirement, etc....
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Sensitivity (False negative - False positives)
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Disadvantages/Advantages
Be prepared to contribute to the class discussion of short term
assays on October 4. Choose your assay on October 2. Review papers will
be handed out on October 7.
List of possible short-term assays to review:
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Salmonella Mutagenicity Assay (Ames Assay)
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Sister Chromatid Exchange Assay
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Chinese Hamster Cell Mutagenesis Assay
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Cell Transformation Assays
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Ecotoxicology Assays
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Sperm Morphology Assay
To get a copy of the short term assay review form:Review
Form