Announcements:


Location

Lectures will be held on Mondays, Wednesdays and Fridays in the Electrical Engineering Building (EEB), Room 045 , from 11:30AM-12:20PM

Lecture Schedule

Week Date Monday Wednesday Friday
1 9/25 - 9/27 No Class Forces I (DB) Forces II (DB)
2 9/30 - 10/4 Forces III (DB) X-Ray Crystallography I (EM) X-Ray Crystallography II (EM)
3 10/7 - 10/11 X-Ray Crystallography III (EM) X-Ray Crystallography IV (EM) Protein Structure I (CV)
4 10/14 - 10/18 Protein Structure II (CV) NMR Spectroscopy I (DB) NMR Spectroscopy II (DB)
5 10/21 - 10/25 Protein Dynamics I (VD) Protein Dynamics II(VD) The RNA World I (AW)
RNA folding movie
6 10/28 - 11/1 The RNA World II (AW) Protein Folding I (DB)  Protein Folding II (DB)
7 11/4 - 11/8 Electron Microscopy (WH) Viruses (WH) The RNA World III (AW)
8 11/11 - 11/15 No Class (Veteran's Day) Signaling and Protein Modification I (NZ) Signaling and Protein Modification II (NZ)
9 11/18 - 11/22 Protein Folding in vivo (DB) Sequence Comparison (DB) Structure Prediction (DB)
10 11/25 - 11/29 NMR III (RK) NMR IV (RK) No Class (Thanksgiving)
11 12/2 - 12/6 Protein Design (DB) Membrane Proteins (WH)  Structure-Based Drug Design (WH)
12 12/10 - 12/14 Exam
Instructors
E-mail
David Baker dabaker@u.washington.edu
Ethan Merritt merritt@u.washington.edu
Valerie Daggett daggett@u.washington.edu
Rachel Klevit klevit@u.washington.edu
Wim Hol wghol@u.washington.edu
Alan Weiner amweiner@u.washington.edu
Christophe Verlinde verlinde@u.washington.edu
Ning Zheng nzheng@u.washington.edu



Homework

All graded homework assignments and FINAL will be returned in class, then put in the Biochemistry Office (HSB J-405)

[ Homework #1 ] Assigned 10/4, due 10/11 in class
Homework #1
Homework #1 Key

[ Homework #2 ] Assigned 10/18, due 10/25 in class
Homework #2
Homework #2 Key

[ Homework #3 ] Assigned 11/15, due 11/22 in class
Homework #3

[ Final Assignment ] Assigned 12/6, due 12/13 at office hours (J-406 from 1-2pm)
Final Assignment
Bauman et al
Nikaido et al

Teaching Assistant
E-mail
Luke Dang
lukedang@uw.edu

Grading

Your final grade will be based on weekly homework assignments (60%), class participation (10%), and the final exam (30%).


Resources

X-Ray Crystallography Section Website

BIOC 530 NMR Resources

Saunders et al

Zhuravleva et al


Office Hours

Office hours are held each week in Health Sciences J-406 on Fridays from 1pm to 2pm. For other times, please email Luke at lukedang@uw.edu to make an appointment.

   

Reading

These books will be on reserve in the Health Sciences Library. Several of them will also be available during office hours along with other relevant texts.

Protein Physics, Alexei Finkelstein, Oleg Ptitsyn
Introduction to Protein Structure, Carl Brenden and John Tooze
Structure and Mechanism in Protein Science, Alan Fersht
Proteins: Structure and Molecular Properties, Thomas Creighton


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