Vitamin D:References


Meta-analyses and reviews

Bouillon R. Vitamin D and health: perspectives from mice and man. J Bone Miner Res 2008;23(7):974-9. Very balanced review

Bischoff-Ferrari HA. Prevention of nonvertebral fractures with oral vitamin D and dose dependency: a meta-analysis of randomized controlled trials. Arch Intern Med 2009;169(6):551-61.

Autier P. Vitamin D supplementation and total mortality: a meta-analysis of randomized controlled trials. Arch Intern Med 2007;167(16):1730-7.

Wei MY. Vitamin D and prevention of colorectal adenoma: a meta-analysis. Cancer Epidemiol Biomarkers Prev 2008;17(11):2958-69.

Tang BM. Use of calcium or calcium in combination with vitamin D supplementation to prevent fractures and bone loss in people aged 50 years and older: a meta-analysis. Lancet 2007;370(9588):657-66.

Holick MF. Vitamin D deficiency. N Engl J Med 2007;357(3):266-81.

Avenell A. Vitamin D and vitamin D analogues for preventing fractures associated with involutional and post-menopausal osteoporosis. Cochrane Database Syst Rev 2005(3):CD000227.

Boonen S. Need for additional calcium to reduce the risk of hip fracture with vitamin d supplementation: evidence from a comparative metaanalysis of randomized controlled trials. J Clin Endocrinol Metab 2007;92(4):1415-23.

Francis RM. Calcium and vitamin D in the prevention of osteoporotic fractures. Qjm 2006;99(6):355-63.

Bischoff-Ferrari HA. Fracture prevention with vitamin D supplementation: a meta-analysis of randomized controlled trials. Jama 2005;293(18):2257-64.

Dhesi JK. The implications of a growing evidence base for drug use in elderly patients. Part 4. Vitamin D and bisphosphonates for fractures and osteoporosis. Br J Clin Pharmacol 2006;61(5):521-8.

Major clinical trials

Lyons RA. Preventing fractures among older people living in institutional care: a pragmatic randomised double blind placebo controlled trial of vitamin D supplementation. Osteoporos Int 2007;18(6):811-8.

Jackson RD. Calcium plus vitamin D supplementation and the risk of fractures. N Engl J Med 2006;354(7):669-83. The results of the Women's Health Initiative, by far the largest and longest clinical trial.

Law M. Vitamin D supplementation and the prevention of fractures and falls: results of a randomised trial in elderly people in residential accommodation. Age Ageing 2006;35(5):482-6.

Porthouse J. Randomised controlled trial of calcium and supplementation with cholecalciferol (vitamin D3) for prevention of fractures in primary care. Bmj 2005;330(7498):1003.

Grant AM. Oral vitamin D3 and calcium for secondary prevention of low-trauma fractures in elderly people (Randomised Evaluation of Calcium Or vitamin D, RECORD): a randomised placebo-controlled trial. Lancet 2005;365(9471):1621-8.

Larsen ER. Vitamin D and calcium supplementation prevents osteoporotic fractures in elderly community dwelling residents: a pragmatic population-based 3-year intervention study. J Bone Miner Res 2004;19(3):370-8.

Trivedi DP. Effect of four monthly oral vitamin D3 (cholecalciferol) supplementation on fractures and mortality in men and women living in the community: randomised double blind controlled trial. Bmj 2003;326(7387):469.

Chapuy MC. Combined calcium and vitamin D3 supplementation in elderly women: confirmation of reversal of secondary hyperparathyroidism and hip fracture risk: the Decalyos II study. Osteoporos Int 2002;13(3):257-64.

Chapuy MC. Effect of calcium and cholecalciferol treatment for three years on hip fractures in elderly women. Bmj 1994;308(6936):1081-2.

Lips P. Vitamin D supplementation and fracture incidence in elderly persons. A randomized, placebo-controlled clinical trial. Ann Intern Med 1996;124(4):400-6.

Anderson FH, Smith HE, Raphael HM, Crozier SR, Cooper C. Ef- fect of annual intramuscular vitamin D3 supplementation on frac- ture risk in 9440 community-living older people: the Wessex frac- ture prevention trial [abstract]. Journal of Bone and Mineral Research 2004;19(Suppl 1):S57

Other

LaCroix AZ. Calcium plus vitamin D supplementation and mortality in postmenopausal women: the Women's Health Initiative calcium-vitamin D randomized controlled trial. J Gerontol A Biol Sci Med Sci 2009;64(5):559-67.

Melamed ML. 25-hydroxyvitamin D levels and the risk of mortality in the general population. Arch Intern Med 2008;168(15):1629-37.

Freedman DM. Serum levels of vitamin D metabolites and breast cancer risk in the prostate, lung, colorectal, and ovarian cancer screening trial. Cancer Epidemiol Biomarkers Prev 2008;17(4):889-94.

Dobnig H. Independent association of low serum 25-hydroxyvitamin d and 1,25-dihydroxyvitamin d levels with all-cause and cardiovascular mortality. Arch Intern Med 2008;168(12):1340-9.

Cranney A. Summary of evidence-based review on vitamin D efficacy and safety in relation to bone health. Am J Clin Nutr 2008;88(2):513S-9S.

Cauley JA. Serum 25-hydroxyvitamin D concentrations and risk for hip fractures. Ann Intern Med 2008;149(4):242-50.

Ahn J. Serum vitamin D concentration and prostate cancer risk: a nested case-control study. J Natl Cancer Inst 2008;100(11):796-804.

Miller PD. Occurrence of hypercalciuria in patients with osteoporosis treated with teriparatide. J Clin Endocrinol Metab 2007;92(9):3535-41.

Binkley N. Low vitamin D status despite abundant sun exposure. J Clin Endocrinol Metab 2007;92(6):2130-5.

Looker AC. Serum 25-hydroxyvitamin d and hip fracture risk in older U.S. white adults. J Bone Miner Res 2008;23(1):143-50.

Garnero P. Associations of vitamin D status with bone mineral density, bone turnover, bone loss and fracture risk in healthy postmenopausal women. The OFELY study. Bone 2007;40(3):716-22.

Liu PT. Toll-like receptor triggering of a vitamin D-mediated human antimicrobial response. Science 2006;311(5768):1770-3.

Christakos S. New insights into the mechanisms involved in the pleiotropic actions of 1,25dihydroxyvitamin D3. Ann N Y Acad Sci 2006;1068:194-203.

Adams JS. Vitamin D as a defensin. J Musculoskelet Neuronal Interact 2006;6(4):344-6.

Bischoff-Ferrari HA. Positive association between 25-hydroxy vitamin D levels and bone mineral density: a population-based study of younger and older adults. Am J Med 2004;116(9):634-9.

Bischoff-Ferrari HA. Effect of Vitamin D on falls: a meta-analysis. Jama 2004;291(16):1999-2006.

Armas LA. Vitamin D2 is much less effective than vitamin D3 in humans. J Clin Endocrinol Metab 2004;89(11):5387-91.

Heaney RP. Functional indices of vitamin D status and ramifications of vitamin D deficiency. Am J Clin Nutr 2004;80(6 Suppl):1706S-9S.

Vitamin D and Cancer

Ahn J. Dairy products, calcium intake, and risk of prostate cancer in the prostate, lung, colorectal, and ovarian cancer screening trial. Cancer Epidemiol Biomarkers Prev 2007;16(12):2623-30.

Autier P. Vitamin D supplementation and total mortality: a meta-analysis of randomized controlled trials. Arch Intern Med 2007;167(16):1730-7.

Bertone-Johnson ER. Prospective studies of dietary vitamin D and breast cancer: more questions raised than answered. Nutr Rev 2007;65(10):459-66.

Chlebowski RT. Calcium plus vitamin D supplementation and the risk of breast cancer. J Natl Cancer Inst 2007;100(22):1581-91.

Cranney A. Effectiveness and safety of vitamin D in relation to bone health. Evid Rep Technol Assess (Full Rep) 2007(158):1-235.

Freedman DM. Prospective study of serum vitamin D and cancer mortality in the United States. J Natl Cancer Inst 2007;99(21):1594-602.

Giovannucci E. Epidemiological evidence for vitamin D and colorectal cancer. J Bone Miner Res 2007;22 Suppl 2:V81-5.

Lappe JM. Vitamin D and calcium supplementation reduces cancer risk: results of a randomized trial. Am J Clin Nutr 2007;85(6):1586-91.

Abbas S. Serum 25-hydroxyvitamin D and risk of post-menopausal breast cancer--results of a large case-control study. Carcinogenesis 2008;29(1):93-9.

Ahn J. Serum vitamin D concentration and prostate cancer risk: a nested case-control study. J Natl Cancer Inst 2008;100(11):796-804.

Bischoff-Ferrari HA. Optimal serum 25-hydroxyvitamin D levels for multiple health outcomes. Adv Exp Med Biol 2008;624:55-71.

Bouillon R. Vitamin D and Human Health: Lessons from Vitamin D Receptor Null Mice. Endocr Rev 2008.

Cannell JJ. Diagnosis and treatment of vitamin D deficiency. Expert Opin Pharmacother 2008;9(1):107-18.

Cherniack EP. Hypovitaminosis D: a widespread epidemic. Geriatrics 2008;63(4):24-30.

Freedman DM. Serum levels of vitamin D metabolites and breast cancer risk in the prostate, lung, colorectal, and ovarian cancer screening trial. Cancer Epidemiol Biomarkers Prev 2008;17(4):889-94.

Giovannucci E. Vitamin D and Cancer Incidence in the Harvard Cohorts. Ann Epidemiol 2008.

Melamed ML. 25-hydroxyvitamin D levels and the risk of mortality in the general population. Arch Intern Med 2008;168(15):1629-37.

Wei MY. Vitamin D and prevention of colorectal adenoma: a meta-analysis. Cancer Epidemiol Biomarkers Prev 2008;17(11):2958-69.

Bolland MJ. Vitamin D insufficiency and health outcomes over 5 y in older women. Am J Clin Nutr 2009;91(1):82-9.

Chiang KC. Fish oil enhances the antiproliferative effect of 1alpha,25-dihydroxyvitamin D3 on liver cancer cells. Anticancer Res 2009;29(9):3591-6.

Chlebowski RT. Caution regarding 25-hydroxyvitamin D monitoring in women with breast cancer. J Clin Oncol 2009;27(24):e72-3; author reply e4.

Crew KD. Association between plasma 25-hydroxyvitamin D and breast cancer risk. Cancer Prev Res (Phila Pa) 2009;2(6):598-604.

McCullough ML. Serum 25-hydroxyvitamin D concentrations and postmenopausal breast cancer risk: a nested case control study in the Cancer Prevention Study-II Nutrition Cohort. Breast Cancer Res 2009;11(4):R64.

Olsen A. Re: Calcium plus vitamin D supplementation and the risk of breast cancer. J Natl Cancer Inst 2009;101(9):690; author reply -1.

Rejnmark L. Reduced prediagnostic 25-hydroxyvitamin D levels in women with breast cancer: a nested case-control study. Cancer Epidemiol Biomarkers Prev 2009;18(10):2655-60.

Simon JA. ACP Journal Club: Review: Evidence for the effectiveness of vitamin D and calcium for reducing CV outcomes, cancer, and death is limited. Ann Intern Med 2009;151(10):JC5-.

Stolzenberg-Solomon RZ. Serum vitamin D and risk of pancreatic cancer in the prostate, lung, colorectal, and ovarian screening trial. Cancer Res 2009;69(4):1439-47.

Tang JY. Inverse association between serum 25(OH) vitamin D levels and non-melanoma skin cancer in elderly men. Cancer Causes Control 2009.

Toriola AT. Serum 25-hydroxyvitamin D and the risk of ovarian cancer. Eur J Cancer 2009;46(2):364-9.

Travis RC. Serum vitamin D and risk of prostate cancer in a case-control analysis nested within the European Prospective Investigation into Cancer and Nutrition (EPIC). Am J Epidemiol 2009;169(10):1223-32.

Yin L. Meta-analysis of longitudinal studies: Serum vitamin D and prostate cancer risk. Cancer Epidemiol 2009;33(6):435-45.

Agborsangaya CB. Serum 25-hydroxyvitamin D at pregnancy and risk of breast cancer in a prospective study. Eur J Cancer 2010;46(3):467-70.

Almquist M. Serum levels of vitamin D, PTH, calcium and breast cancer risk - a prospective nested case-control study. Int J Cancer 2010.

DIPART Group. Patient level pooled analysis of 68 500 patients from seven major vitamin D fracture trials in US and Europe. Bmj 2010;340:b5463.

Jenab M. Association between pre-diagnostic circulating vitamin D concentration and risk of colorectal cancer in European populations:a nested case-control study. Bmj 2010;340:b5500.

Park SY. Plasma 25-hydroxyvitamin D and prostate cancer risk: The Multiethnic Cohort. Eur J Cancer 2010.

Woolcott CG. Plasma 25-hydroxyvitamin D levels and the risk of colorectal cancer: the multiethnic cohort study. Cancer Epidemiol Biomarkers Prev 2010 ;19(1):130-4.

Updated 3/3/10