Bone Remodeling Animations

These can be used for educational purposes. They are all now .mp4 files. Please include a citation to the web site, and I would also appreciate it if you sent an email message about how you are using them.

Physiology of bone at one Basic Metabolic Unit

Quiescent
Microcrack
Canopy
Stromal
Fusion
Resorption
Apoptosis
Formation
One BMU

Bone Turnover

The second set of animations are based on histomorphometric measurements, where the mineralized bone is green and the osteoid is red. This is approximately what you would see in 2mm of trabecular bone. The volume, surfaces, and formation rates are drawn to scale. The darkness of the green is meant to show approximate mineralization density but is not directly related to the density measurements.

Normal remodeling
Menopause
SERM/estrogen
Bisphosphonate
Teriparatide
Denosumab
Romosozumab

Here is a powerpoint slideset part 1 and part 2 with the bone remodeling sequence and various conditions (normal, menopause, and treatments). It may be necessary to first download the .mp4 files.

The Growth Plate

These two movies have narration - I just figured out that I can screen record the old Flash files that can't directly convert!

Growth Plate part 1
Growth Plate part 2

Updated 11/9/21