Biochemical markers reference list

Akesson, K.(1995). Assessment of biochemical markers of bone metabolism in relation to the occurrence of fracture: a retrospective and prospective population- based study of women. J Bone Miner Res 10(11): 1823-9.

Akesson, K.(1998). Effects of short-term calcium depletion and repletion on biochemical markers of bone turnover in young adult women. J Clin Endocrinol Metab 83(6): 1921-7.

Alexandersen, P.(1995). The effect of menopause and hormone replacement therapy on bone alkaline phosphatase. Scand J Clin Lab Invest 55(7): 571-6.

Amama, E. A.(1998). The effect of gonadotropin-releasing hormone agonist on type I collagen C-telopeptide and N-telopeptide: the predictive value of biochemical markers of bone turnover. J Clin Endocrinol Metab 83(2): 333-8.

Bauer, D. C.(1999). Biochemical markers of bone turnover and prediction of hip bone loss in older women: the study of osteoporotic fractures. J Bone Miner Res 14(8): 1404-10.

Beck-Jensen, J. E.(1997). A single measurement of biochemical markers of bone turnover has limited utility in the individual person. Scand J Clin Lab Invest 57(4): 351-9.

Bennell, K. L.(1998). A 12-month prospective study of the relationship between stress fractures and bone turnover in athletes. Calcif Tissue Int 63(1): 80-5.

Bollen, A. M.(1994). Bone resorption rates in children monitored by the urinary assay of collagen type I cross-linked peptides. Bone 15(1): 31-4.

Bollen, A. M.(1995). Circadian variation in urinary excretion of bone collagen cross-links. J Bone Miner Res 10(12): 1885-90.

Bollen, A. M.(1997). Longitudinal evaluation of a bone resorption marker in elderly subjects. Osteoporos Int 7(6): 544-9.

Bonde, M.(1995). Applications of an enzyme immunoassay for a new marker of bone resorption (CrossLaps): follow-up on hormone replacement therapy and osteoporosis risk assessment. J Clin Endocrinol Metab 80(3): 864-8.

Bonde, M.(1997). Measurement of bone degradation products in serum using antibodies reactive with an isomerized form of an 8 amino acid sequence of the C-telopeptide of type I collagen. J Bone Miner Res 12(7): 1028-34.

Borderie, D.(1998). Biochemical markers as predictors of bone mineral density changes after GnRH agonist treatment. Calcif Tissue Int 62(1): 21-5.

Castro, B. d.(1999). Monitoring alendronate therapy for osteoporosis. J Bone Miner Res 14(4): 602-8.

Chen, J. T.(1996). Serum N-terminal osteocalcin is a good indicator for estimating responders to hormone replacement therapy in postmenopausal women. J Bone Miner Res 11(11): 1784-92.

Cheng, S.(1996). Serum and urine markers of type I collagen metabolism in elderly women with high and low bone mineral density. Eur J Clin Invest 26(3): 186-91.

Chesnut, C. H. r.(1997). Hormone replacement therapy in postmenopausal women: urinary N-telopeptide of type I collagen monitors therapeutic effect and predicts response of bone mineral density. Am J Med 102(1): 29-37.

Chiu, K. M.(1999). Changes in bone resorption during the menstrual cycle. J Bone Miner Res 14(4): 609-15.

Christgau, S.(1998). Clinical evaluation of the Serum CrossLaps One Step ELISA, a new assay measuring the serum concentration of bone-derived degradation products of type I collagen C-telopeptides. Clin Chem 44(11): 2290-300.

Cohen, F. J.(1998). Geographic differences in bone turnover: data from a multinational study in healthy postmenopausal women. Calcif Tissue Int 63(4): 277-82.

Colwell, A.(1996). The renal clearance of free and conjugated pyridinium cross-links of collagen. J Bone Miner Res 11(12): 1976-80.

Cosman, F.(1996). Bone density change and biochemical indices of skeletal turnover. Calcif Tissue Int 58(4): 236-43.

De Souza, M. J.(1997). Bone health is not affected by luteal phase abnormalities and decreased ovarian progesterone production in female runners [see comments]. J Clin Endocrinol Metab 82(9): 2867-76.

Di Somma, C.(1998). Effectiveness of chronic treatment with alendronate in the osteoporosis of Cushing's disease. Clin Endocrinol (Oxf) 48(5): 655-62.

Di Somma, C.(1998). Bone marker and bone density responses to dopamine agonist therapy in hyperprolactinemic males. J Clin Endocrinol Metab 83(3): 807-13.

Dmowski, W. P.(1996 ). Excretion of urinary N-telopeptides reflects changes in bone turnover during ovarian suppression and indicates individually variable estradiol threshold for bone loss. Fertil Steril 66(6): 929-36.

Dresner-Pollak, R.(1996). Biochemical markers of bone turnover reflect femoral bone loss in elderly women. Calcif Tissue Int 59(5): 328-33.

Eastell, R.(1997). Biochemical markers of bone resorption compared with estimates of bone resorption from radiotracer kinetic studies in osteoporosis. J Bone Miner Res 12(1): 59-65.

Ebeling, P. R.(1996). Bone turnover markers and bone density across the menopausal transition. J Clin Endocrinol Metab 81(9): 3366-71.

Eriksen, E. F.(1993 ). Serum markers of type I collagen formation and degradation in metabolic bone disease: correlation with bone histomorphometry. J Bone Miner Res 8(2): 127-32.

Fatayerji, D.(1999). Age-related changes in bone turnover in men. J Bone Mineral Res 14: 1203-1210.

Gallagher, J. C.(1998). Calciotropic hormones and bone markers in the elderly. J Bone Miner Res 13(3): 475-82.

Garnero, P.(1993). Assessment of the serum levels of bone alkaline phosphatase with a new immunoradiometric assay in patients with metabolic bone disease. J Clin Endocrinol Metab 77: 1046-53.

Garnero, P.(1994). Comparison of new biochemical markers of bone turnover in late postmenopausal osteoporotic women in response to alendronate treatment. J Clin Endocrinol Metab 79(6): 1693-700.

Garnero, P.(1996). Markers of bone resorption predict hip fracture in elderly women: the EPIDOS Prospective Study. J Bone Miner Res 11(10): 1531-8.

Garnero, P.(1996). Increased bone turnover in late postmenopausal women is a major determinant of osteoporosis. J Bone Miner Res 11(3): 337-49.

Garnero, P.(1998). Do markers of bone resorption add to bone mineral density and ultrasonographic heel measurement for the prediction of hip fracture in elderly women? The EPIDOS prospective study. Osteoporos Int 8(6): 563-9.

Garnero, P.(1999). Markers of bone turnover predict postmenopausal forearm bone loss over 4 years: the OFELY study. J Bone Miner Res 14(9): 1614-21.

Garnero, P.(1999). A model to monitor the efficacy of alendronate treatment in women with osteoporosis using a biochemical marker of bone turnover. Bone 24(6): 603-9.

Gerrits, M. I.(1998). Comparison of urinary bone resorption markers in women of 40-70 years; day-to-day and long-term variation in individual subjects. Maturitas 30(3): 247-55.

Gertz, B. J.(1994). Monitoring bone resorption in early postmenopausal women by an immunoassay for cross-linked collagen peptides in urine. J Bone Miner Res 9(2): 135-42.

Gertz, B. J.(1998). Application of a new serum assay for type I collagen cross-linked N-telopeptides: assessment of diurnal changes in bone turnover with and without alendronate treatment. Calcif Tissue Int 63(2): 102-6.

Gertz, B. J.(1998). Application of a new serum assay for type I collagen cross-linked N-telopeptides: assessment of diurnal changes in bone turnover with and without alendronate treatment. Calcif Tissue Int 63(2): 102-6.

Ginty, F.(1998). The effect of dietary sodium intake on biochemical markers of bone metabolism in young women. Br J Nutr 79(4): 343-50.

Gonnelli, S.(1996). Bone alkaline phosphatase measured with a new immunoradiometric assay in patients with metabolic bone diseases. Eur J Clin Invest 26(5): 391-6.

Gonnelli, S.(1997). The usefulness of bone turnover in predicting the response to transdermal estrogen therapy in postmenopausal osteoporosis. J Bone Miner Res 12(4): 624-31.

Gorai, I.(1995). Urinary biochemical markers for bone resorption during the menstrual cycle. Calcif Tissue Int 57(2): 100-4.

Gorai, I.(1997 ). Specific changes of urinary excretion of cross-linked N-telopeptides of type I collagen in pre- and postmenopausal women: correlation with other markers of bone turnover. Calcif Tissue Int 60(4): 317-22.

Gorai, I.(1998). Serum soluble interleukin-6 receptor and biochemical markers of bone metabolism show significant variations during the menstrual cycle. J Clin Endocrinol Metab 83(2): 326-32.

Greenspan, S. L.(1997). Diurnal variation of bone mineral turnover in elderly men and women. Calcif Tissue Int 60(5): 419-23.

Greenspan, S. L.(1998). Early changes in biochemical markers of bone turnover predict the long- term response to alendronate therapy in representative elderly women: a randomized clinical trial. J Bone Miner Res 13(9): 1431-8.

Hannon, R.(1998). Response of biochemical markers of bone turnover to hormone replacement therapy: impact of biological variability [see comments]. J Bone Miner Res 13(7): 1124-33.

Hanson, D. A.(1992 ). A specific immunoassay for monitoring human bone resorption: quantitation of type I collagen cross-linked N-telopeptides in urine. J Bone Miner Res 7(11): 1251-8.

Heikkinen, A. M.(1997). Biochemical bone markers and bone mineral density during postmenopausal hormone replacement therapy with and without vitamin D3: a prospective, controlled, randomized study. J Clin Endocrinol Metab 82(8): 2476-82.

Hesley, R. P.(1998). Monitoring estrogen replacement therapy and identifying rapid bone losers with an immunoassay for deoxypyridinoline. Osteoporos Int 8(2): 159-64.

Keen, R. W.(1996). Can biochemical markers predict bone loss at the hip and spine?: a 4- year prospective study of 141 early postmenopausal women. Osteoporos Int 6(5): 399-406.

Kerstetter, J. E.(1999). Changes in bone turnover in young women consuming different levels of dietary protein. J Clin Endocrinol Metab 84(3): 1052-5.

Khan, S. A.(1997). Elimination and biochemical responses to intravenous alendronate in postmenopausal osteoporosis. J Bone Miner Res 12(10): 1700-7.

Khosla, S.(1997). Effects of age and estrogen status on serum parathyroid hormone levels and biochemical markers of bone turnover in women: A population-based study. J Clin Endocrinol Metab 82: 1522-1527.

Khosla, S.(1998). Relationship of serum sex steroid levels and bone turnover markers with bone mineral density in men and women: a key role for bioavailable estrogen. J Clin Endocrinol Metab 83(7): 2266-74.

Knott, L.(1998). Collagen cross-links in mineralizing tissues: a review of their chemistry, function, and clinical relevance. Bone 22(3): 181-7.

Krall, E. A.(1997). Bone mineral density and biochemical markers of bone turnover in healthy elderly men and women. J Gerontol A Biol Sci Med Sci 52(2): M61-7.

Krebs, N. F.(1997). Bone mineral density changes during lactation: maternal, dietary, and biochemical correlates. Am J Clin Nutr 65(6): 1738-46.

Kress, B. C.(1999). Use of bone alkaline phosphatase to monitor alendronate therapy in individual postmenopausal osteoporotic women. Clin Chem 45(7): 1009-17.

Kusec, V.(1998). Biochemical markers of bone metabolism in postmenopausal women--the effect of hormone replacement therapy and smoking. Croat Med J 39(1): 23-7.

Kyd, P. A.(1998). Clinical usefulness of bone alkaline phosphatase in osteoporosis. Ann Clin Biochem 35(Pt 6): 717-25.

Kyd, P. A.(1999). Clinical usefulness of biochemical resorption markers in osteoporosis. Ann Clin Biochem 36(Pt 4): 483-91.

Lopez, J. M.(1996). Bone turnover and density in healthy women during breastfeeding and after weaning. Osteoporos Int 6(2): 153-9.

Marcus, R.(1999). The relationship of biochemical markers of bone turnover to bone density changes in postmenopausal women: results from the Postmenopausal Estrogen/Progestin Interventions (PEPI) trial. J Bone Miner Res 14(9): 1583-95.

Marowska, J.(1996). Pyridinium crosslinks of collagen as a marker of bone resorption rates in children and adolescents: normal values and clinical application. Bone 19(6): 669-77.

Massafra, C.(1999). Androgens and osteocalcin during the menstrual cycle. J Clin Endocrinol Metab 84: 971-974.

Matsumoto, T.(1997). Bone density and bone metabolic markers in active collegiate athletes: findings in long-distance runners, judoists, and swimmers. Int J Sports Med 18(6): 408-12.

Melton, L. J., 3rd(1997). Relationship of bone turnover to bone density and fractures. J Bone Miner Res 12(7): 1083-91.

Minisola, S.(1998). Bone turnover and its relationship with bone mineral density in pre- and postmenopausal women with or without fractures. Maturitas 29(3): 265-70.

Mora, S.(1998). Urinary markers of bone turnover in healthy children and adolescents: age-related changes and effect of puberty. Calcif Tissue Int 63(5): 369-74.

Mora S(1999). Biochemical markers of bone turnover and the volume and the density of bone in children at different stages of sexual development. J Bone Miner Res 14(1664-1671).

Nielsen, H. K.(1990). Changes in biochemical markers of osteoblastic activity during the menstrual cycle. J Clin Endocrinol Metab 70(5): 1431-7.

Orwoll, E. S.(1998). Collagen N-telopeptide excretion in men: the effects of age and intrasubject variability. J Clin Endocrinol Metab 83(11): 3930-5.

Oxlund, H.(1996). Reduced concentration of collagen reducible cross links in human trabecular bone with respect to age and osteoporosis. Bone 19(5): 479-84.

Panteghini, M.(1995). Biological variation in bone-derived biochemical markers in serum. Scand J Clin Lab Invest 55(7): 609-16.

Parviainen, M. T.(1999). Urinary bone resorption markers in monitoring treatment of symptomatic osteoporosis. Clin Chim Acta 279(1-2): 145-54.

Patel, S.(1999). Early effects of hormone replacement therapy on bone. Bone 24(3): 245-8.

Peichl, P.(1998). Association between female sex hormones and biochemical markers of bone turnover in peri- and postmenopausal women. Calcif Tissue Int 62(5): 388-94.

Peris, P.(1999). Biochemical markers of bone turnover after surgical menopause and hormone replacement therapy. Bone 25: 349-353.

Pollak, R. D.(1998). Femoral neck osteopenia in patients with inflammatory bowel disease. Am J Gastroenterol 93(9): 1483-90.

Prentice, A.(1998). Biochemical markers of calcium and bone metabolism during 18 months of lactation in Gambian women accustomed to a low calcium intake and in those consuming a calcium supplement [see comments]. J Clin Endocrinol Metab 83(4): 1059-66.

Prestwood, K. M.(1994). The short-term effects of conjugated estrogen on bone turnover in older women. J Clin Endocrinol Metab 79(2): 366-71.

Prior, J. C.(1997). Premenopausal ovariectomy-related bone loss: a randomized, double- blind, one-year trial of conjugated estrogen or medroxyprogesterone acetate. J Bone Miner Res 12(11): 1851-63.

Randall, A. G.(1996). Comparison of biochemical markers of bone turnover in Paget disease treated with pamidronate and a proposed model for the relationships between measurements of the different forms of pyridinoline cross-links. J Bone Miner Res 11(8): 1176-84.

Ravn, P.(1996). High bone turnover is associated with low bone mass in both pre- and postmenopausal women. Bone 19(3): 291-8.

Ravn, P.(1997). High bone turnover is associated with low bone mass and spinal fracture in postmenopausal women. Calcif Tissue Int 60(3): 255-60.

Ravn, P.(1998). Changes in biochemical markers and bone mass after withdrawal of ibandronate treatment: prediction of bone mass changes during treatment. Bone 22(5): 559-64.

Ravn, P.(1999). Monitoring of alendronate treatment and prediction of effect on bone mass by biochemical markers in the early postmenopausal intervention cohort study. J Clin Endocrinol Metab 84(7): 2363-8.

Ravn, P.(1999). Biochemical markers can predict the response in bone mass during alendronate treatment in early postmenopausal women. Alendronate Osteoporosis Prevention Study Group. Bone 24(3): 237-44.

Reginster, J. Y.(1997). Prediction of bone loss rate in healthy postmenopausal women. Calcif Tissue Int 60(3): 261-4.

Register, T. C.(1997). Oral contraceptive treatment inhibits the normal acquisition of bone mineral in skeletally immature young adult female monkeys. Osteoporos Int 7(4): 348-53.

Rosen, H. N.(1994 ). Specificity of urinary excretion of cross-linked N-telopeptides of type I collagen as a marker of bone turnover. Calcif Tissue Int 54(1): 26-9.

Rosen, C. J.(1997). The predictive value of biochemical markers of bone turnover for bone mineral density in early postmenopausal women treated with hormone replacement or calcium supplementation [see comments]. J Clin Endocrinol Metab 82(6): 1904-10.

Rosen, H. N.(1998). Utility of biochemical markers of bone turnover in the follow-up of patients treated with bisphosphonates. Calcif Tissue Int 63(5): 363-8.

Rosenquist, C.(1998). Serum CrossLaps One Step ELISA. First application of monoclonal antibodies for measurement in serum of bone-related degradation products from C-terminal telopeptides of type I collagen. Clin Chem 44(11): 2281-9.

Ross, P. D.(1998). Rapid bone loss is associated with increased levels of biochemical markers. J Bone Miner Res 13(2): 297-302.

Saarto, T.(1998). Aminoterminal propeptide of type I procollagen (PINP) correlates to bone loss and predicts the efficacy of antiresorptive therapy in pre- and post-menopausal non-metastatic breast cancer patients. Br J Cancer 78(2): 240-5.

Scariano, J. K.(1998). Serum levels of cross-linked N-telopeptides and aminoterminal propeptides of type I collagen indicate low bone mineral density in elderly women. Bone 23(5): 471-7.

Schlemmer, A.(1993). Possible variation in bone resorption during the normal menstrual cycle. Acta Endocrinol (Copenh) 129(5): 388-92.

Schlemmer, A.(1999). Acute fasting diminishes the circadian rhythm of biochemical markers of bone resorption. Eur J Endocrinol 140(4): 332-7.

Schneider, D. L.(1997 9). Urinary N-telopeptide levels discriminate normal, osteopenic, and osteoporotic bone mineral density [see comments]. Arch Intern Med 157(11): 1241-5.

Seibel, M. J.(1996). Serum immunoreactive bone sialoprotein as a new marker of bone turnover in metabolic and malignant bone disease. J Clin Endocrinol Metab 81(9): 3289-94.

Shaarawy, M.(1999). Biomarkers of bone turnover and bone mineral density in hyperprolactinemic amenorrheic women. Clin Chem Lab Med 37(4): 433-8.

Silvennoinen, J.(1996). Increased degradation of type I collagen in patients with inflammatory bowel disease. Gut 38(2): 223-8.

Simberg, N.(1996). High bone density in hyperandrogenic women: effect of gonadotropin- releasing hormone agonist alone or in conjunction with estrogen- progestin replacement. J Clin Endocrinol Metab 81(2): 646-51.

Slemenda, C. W.(1997). Reduced rates of skeletal remodeling are associated with increased bone mineral density during the development of peak skeletal mass. J Bone Miner Res 12(4): 676-82.

Sone, T.(1995). Urinary excretion of type I collagen crosslinked N-telopeptides in healthy Japanese adults: age- and sex-related changes and reference limits. Bone 17(4): 335-9.

Taga, M.(1998). The effect of hormone replacement therapy in postmenopausal women on urinary C-telopeptide and N-telopeptide of type I collagen, new markers of bone resorption. J Endocrinol Invest 21(3): 154-9.

Tobias, J. H.(1996). Aminohexane bisphosphonate suppresses bone turnover in postmenopausal women more rapidly than oestrogen-gestagen therapy. Br J Rheumatol 35(7): 636-41.

Weaver, C. M.(1997). Quantification of biochemical markers of bone turnover by kinetic measures of bone formation and resorption in young healthy females. J Bone Miner Res 12(10): 1714-20.

Weiss, S. R.(1999). A randomized controlled trial of four doses of transdermal estradiol for preventing postmenopausal bone loss. Transdermal Estradiol Investigator Group. Obstet Gynecol 94(3): 330-6.

Woitge, H. W.(1998). Seasonal variation of biochemical indexes of bone turnover: results of a population-based study. J Clin Endocrinol Metab 83(1): 68-75.

Woitge, H.(1999). Novel serum markers of bone resorption: Clinical assessment and comparison with established urinary indices. J Bone Miner Res 14: 792-801.

Yasumizu, T.(1998). Bone metabolism after human parturition and the effect of lactation: longitudinal analysis of serum bone-related proteins and bone mineral content of the lumbar spine. Endocr J 45(5): 679-86.

Yilmaz, N.(1999). Diagnostic value of biochemical markers of bone turnover and postmenopausal osteoporosis. Clin Chem Lab Med 37(2): 137-43.

Zanae, M.(1997). Procollagen propeptide and pyridinium cross-links as markers of type I collagen turnover: sex- and age-related changes in healthy children. J Clin Endocrinol Metab 82: 2971-7.

Zhan, Z.(1999). Urinary pyridinoline and deoxypyridinoline as bone metabolic markers in predicting therapeutic effects of estrogen and alfacalcidol in women with osteoporosis. J Bone Miner Metab 17(2): 113-8.


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