Langerhans Cells

Key concept

Langerhans cells are dendritic cells derived from the mesenchyme. They will be antigen processing and presentation cells in the mature epidermis. They are present in epidermis early in the 6th week of gestation.

Bullet Summary

• Week 6: Langerhans cells appear in the epidermis
• Week 10: Birbeck granules appear
• Week 26: Langerhans cells increase in numbers

To study Langerhans cells over time click on one of the buttons below:

Week 6
Week 10
Week 26