Key concept

The periderm is a superficial layer of cells which develops from the primordial single-cell-layered epidermis and forms a transient covering for the epidermis during much of the remainder of its development. Periderm is a unique feature of developing epidermis; no similar structure occurs in the development of other epithelia.

Bullet Summary


The periderm goes through distinct developmental phases and is ultimately sloughed into the amniotic fluid when differentiation of the underlying epidermal layers is complete. The function of the periderm is not known, but is thought to be related to transport/exchange between the fetus and the amniotic fluid.

To see how the periderm develops and to study the morphologic changes that suggest a transport/exchange function for this epithelium click on one of the buttons below:

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