med 610 clinical respiratory diseases & critcare med

Pulmonary Function Testing

Case 6

A 30 year-old woman presents for evaluation of dyspnea on exertion which has been present for 2 months. She is a life-long non-smoker with no prior history of asthma or other pulmonary problems. She works as a receptionist at a publishing company. She has two cats and several parakeets at home.

Her pulmonary function testing is as follows:

  Pre-Bronchodilator (BD) Post- BD
Test Actual Predicted % Predicted Actual % Change
FVC (L) 1.73 4.37 40 1.79 4
FEV1 (L) 1.57 3.65 43 1.58 0
FEV1/FVC (%) 91 84   88 - 3
RV (L) 1.01 1.98 51    
TLC (L) 2.68 6.12 44    
RV/TLC (%) 38 30      
DLCO* corr 5.13 32.19 16    
*DLCO is measured in ml/min/mmHg
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Her flow volume loops is as follows:

flow volume loop graph

 

Describe the pattern of abnormality, if one is present.

Grade the severity of the abnormality.

Generate a differential diagnosis for the observed abnormality.

 

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