med 610 clinical respiratory diseases & critcare med

Pulmonary Function Testing

Case 7

A 73 year-old man presents with progressive dyspnea on exertion over the past one year. He reports a dry cough but no wheezes, sputum production, fevers or hemoptysis. He is a life-long non-smoker and worked as a lawyer until retiring 3 years ago. He likes to hunt and fish in his leisure time.

His pulmonary function testing is as follows:

  Pre-Bronchodilator (BD)
Test Actual Predicted % Predicted
FVC (L) 1.57 4.46 35
FEV1 (L) 1.28 3.39 38
FEV1/FVC (%) 82 76  
FRC 1.73 3.80 45
RV (L) 1.12 2.59 43
TLC (L) 2.70 6.45 42
RV/TLC (%) 41 42  
DLCO* corr 5.06 31.64 16
*DLCO is measured in ml/min/mmHg
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His flow volume loops is as follows:

flow volume loop graph

 

Describe the pattern of abnormality, if one is present.

Grade the severity of the abnormality.

Generate a differential diagnosis for the observed abnormality.

 

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